Advanced nuclear fuel cycles to improve the safety, sustainability and economics of nuclear energy are being investigated worldwide. Partitioning and transmutation (P&T) is one of the candidate technologies to help reduce the heat, radiotoxicity and volume of radioactive waste. Recent developments indicate the need for embedding P&T strategies into advanced fuel cycles considering both waste management and economic issues. In this context, the Nuclear Energy Agency (NEA) has organised a series of biennial information exchange meetings since 1990 to provide experts with a forum to present and discuss stateof- the-art developments in the field of P&T. The previous meetings were held in Mito (Japan) in 1990, at Argonne National Laboratory (ANL) (United States) in 1992, in Cadarache (France) in 1994, in Mito (Japan) in 1996, in Mol (Belgium) in 1998, in Madrid (Spain) in 2000, in Jeju (Korea) in 2002, in Las Vegas (United States) in 2004, in Nîmes (France) in 2006, in Mito (Japan) in 2008, in San Francisco (United States) in 2010, in Prague (Czech Republic) in 2012, in Seoul (Korea) in 2014, and in San Diego (United States) in 2016. They were co-sponsored by the European Commission (EC) and the International Atomic Energy Agency (IAEA). The 15th Information Exchange Meeting was held in Manchester (United Kingdom) on 30 September - 3 October 2018, hosted by the National Nuclear Laboratory (NNL). The meeting comprised a plenary session on national and international programmes followed by technical sessions and a poster session covering various aspects of P&T and advanced fuel cycles. The information exchange meetings on P&T form a part of the NEA programme of work in the field of advanced nuclear fuel cycles. These proceedings include extended abstracts and papers presented at the 15th Information Exchange Meeting. The opinions expressed are those of the authors only and do not necessarily reflect the views of the NEA or its member countries.