Managing the ageing of fuel cycle facilities (FCFs) means, as for other nuclear installations, ensuring the availability of required safety functions throughout their service life while taking into account the changes that occur with time and use. This technical opinion paper identifies a set of good practices by benchmarking strategies and good practices on coping with physical ageing and obsolescence from the facility design stage until decommissioning. It should be of particular interest to nuclear safety regulators, fuel cycle facilities operators and fuel cycle researchers.