NESC1088 UMIBIO.
UMIBIO, U Mill Bioassay Dosimetry Model
NAME OR DESIGNATION OF PROGRAM, COMPUTER, DESCRIPTION OF PROGRAM OR FUNCTION, METHOD OF SOLUTION, RESTRICTIONS ON THE COMPLEXITY OF THE PROBLEM, TYPICAL RUNNING TIME, UNUSUAL FEATURES OF THE PROGRAM, RELATED AND AUXILIARY PROGRAMS, STATUS, REFERENCES, MACHINE REQUIREMENTS, LANGUAGE, OPERATING SYSTEM UNDER WHICH PROGRAM IS EXECUTED, OTHER PROGRAMMING OR OPERATING INFORMATION OR RESTRICTIONS, NAME AND ESTABLISHMENT OF AUTHORS, MATERIAL, CATEGORIES
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3. DESCRIPTION OF PROGRAM OR FUNCTION
UMIBIO is an internal dosimetry model developed for estimation of the urinary concentration of natural uranium excreted at various times after an inhalation exposure to yellowcake (dried at high and at low temperatures) or ore dust. Calculations are based either on the single exposure intake variable or for continuous exposure on the intake rate variable. The user may change the default intake variables, specify single versus continuous exposure and one or both exponential terms for the systemic calculations.
UMIBIO is an internal dosimetry model developed for estimation of the urinary concentration of natural uranium excreted at various times after an inhalation exposure to yellowcake (dried at high and at low temperatures) or ore dust. Calculations are based either on the single exposure intake variable or for continuous exposure on the intake rate variable. The user may change the default intake variables, specify single versus continuous exposure and one or both exponential terms for the systemic calculations.
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4. METHOD OF SOLUTION
UMIBIO uses the model developed by the Task Group on Lung Dynamics of the International Commission on Radiological Protection (ICRP) to describe the deposition and retention of inhaled radioactive material in the human respiratory tract and its clearance into the blood. The metabolic model assumes that 11 percent of the uranium reaching the blood is deposited in kidney tissues and is subsequently excreted with a 15-day half-life. It is also assumed that 67 percent of the uranium reaching the blood is excreted within 24 hours without being deposited in any organ. The systemic uptake by all other organs is 22 percent; this uranium is subsequently released back to the blood in accordance with a power function which may be represented by the sum of two exponential functions as recommended in ICRP-30.
UMIBIO uses the model developed by the Task Group on Lung Dynamics of the International Commission on Radiological Protection (ICRP) to describe the deposition and retention of inhaled radioactive material in the human respiratory tract and its clearance into the blood. The metabolic model assumes that 11 percent of the uranium reaching the blood is deposited in kidney tissues and is subsequently excreted with a 15-day half-life. It is also assumed that 67 percent of the uranium reaching the blood is excreted within 24 hours without being deposited in any organ. The systemic uptake by all other organs is 22 percent; this uranium is subsequently released back to the blood in accordance with a power function which may be represented by the sum of two exponential functions as recommended in ICRP-30.
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10. REFERENCES
- International Commission on Radiological Protection, Limits for
Intakes of Radionuclides by Workers,
ICRP Publication 30, Pergamon Press, New York, July 1978.
- International Commission on Radiological Protection,
Recommendations of the International Commission on Radiological
Protection,
ICRP Publication 26, Pergamon Press, New York, January 1977.
- International Commission on Radiological Protection, Limits for
Intakes of Radionuclides by Workers,
ICRP Publication 30, Pergamon Press, New York, July 1978.
- International Commission on Radiological Protection,
Recommendations of the International Commission on Radiological
Protection,
ICRP Publication 26, Pergamon Press, New York, January 1977.
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14. OTHER PROGRAMMING OR OPERATING INFORMATION OR RESTRICTIONS
The proprietary CA-DISSPLA graphics software (see http://www.gaeinc.com), used by UMIBIO, is not included. If CA-DISSPLA is not available or graphical output is not required, the call to subroutine DISPLT should be eliminated from the MAIN routine.
The proprietary CA-DISSPLA graphics software (see http://www.gaeinc.com), used by UMIBIO, is not included. If CA-DISSPLA is not available or graphical output is not required, the call to subroutine DISPLT should be eliminated from the MAIN routine.
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Keywords: inhalation, radiation doses, respiratory system, uranium.